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1

Atomic structure of the MAP kinase ERK2 at 2.3 Å resolution

Zhang, Faming, Strand, Arne, Robbins, David, Cobb, Melanie H., Goldsmith, Elizabeth J.

Journal:

Year:

1994

File:

PDF, 1.16 MB

1994

2

Structural basis of inhibitor selectivity in MAP kinases

Zhulun Wang, Bertram J Canagarajah, Jeffrey C Boehm, Skouki Kassisà, Melanie H Cobb, Peter R Young, Sherin Abdel-Meguid, Jerry L Adams, Elizabeth J Goldsmith

Journal:

Year:

1998

Language:

english

File:

PDF, 1.79 MB

english, 1998

3

Activation Mechanism of the MAP Kinase ERK2 by Dual Phosphorylation

Bertram J. Canagarajah, Andrei Khokhlatchev, Melanie H. Cobb, Elizabeth J. Goldsmith

Journal:

Year:

1997

Language:

english

File:

PDF, 2.09 MB

english, 1997

4

Pharmacological inhibitors of MAPK pathways

Jessie M. English, Melanie H. Cobb

Journal:

Trends in Pharmacological Sciences

Year:

2002

Language:

english

File:

PDF, 63 KB

english, 2002

5

Insulin Promoter-Driven Gaussia Luciferase-Based Insulin Secretion Biosensor Assay for Discovery of β-Cell Glucose-Sensing Pathways

Kalwat, Michael A., Wichaidit, Chonlarat, Nava Garcia, Alejandra Y., McCoy, Melissa K., McGlynn, Kathleen, Hwang, In Hyun, MacMillan, John B., Posner, Bruce A., Cobb, Melanie H.

Journal:

Year:

2016

Language:

english

File:

PDF, 1.54 MB

english, 2016

6

Mechanisms of the Amplifying Pathway of Insulin Secretion in the β Cell

Kalwat, Michael A., Cobb, Melanie

Journal:

Pharmacology & Therapeutics

Year:

2017

Language:

english

File:

PDF, 1.02 MB

english, 2017

7

Assaying Protein Kinase Activity with Radiolabeled ATP

Karra, Aroon S., Stippec, Steve, Cobb, Melanie H.

Journal:

Journal of Visualized Experiments

Year:

2017

Language:

english

File:

PDF, 414 KB

english, 2017

8

MEKK1 interacts with α-actinin and localizes to stress fibers and focal adhesions

Lori B. Christerson, Colleen A. Vanderbilt, Melanie H. Cobb

Journal:

Year:

1999

Language:

english

File:

PDF, 799 KB

english, 1999

9

Mutations and polymorphisms in hemoglobin genes and the risk of pulmonary hypertension and death in sickle cell disease

James G. Taylor VI, Diana Ackah, Crystal Cobb, Nick Orr, Melanie J. Percy, Vandana Sachdev, Roberto Machado, Oswaldo Castro, Gregory J. Kato, Stephen J. Chanock, Mark T. Gladwin

Journal:

American Journal of Hematology

Year:

2008

Language:

english

File:

PDF, 371 KB

english, 2008

10

ChemInform Abstract: MAP Kinases

Zhu Chen, Tara Beers Gibson, Fred Robinson, Loraine Silvestro, Gray Pearson, Bing-e Xu, Angelique Wright, Colleen Vanderbilt, Melanie H. Cobb

Journal:

Year:

2001

File:

PDF, 25 KB

2001

11

Effect of titanium dioxide nanomaterials and ultraviolet light coexposure on African clawed frogs (Xenopus laevis)

Junling Zhang, Mike Wages, Stephen B. Cox, Jonathan D. Maul, Yujia Li, Melanie Barnes, Louisa Hope-Weeks, George P. Cobb

Journal:

Environmental Toxicology and Chemistry

Year:

2012

Language:

english

File:

PDF, 549 KB

english, 2012

12

p115 Rho GTPase activating protein interacts with MEKK1

Lori B. Christerson, Ewen Gallagher, Colleen A. Vanderbilt, Angelique W. Whitehurst, Clark Wells, Roxana Kazempour, Paul C. Sternweis, Melanie H. Cobb

Journal:

Journal of Cellular Physiology

Year:

2002

Language:

english

File:

PDF, 448 KB

english, 2002

13

Ultrastructural analysis of the organization and distribution of insulin receptors on the surface of 3T3-L1 adipocytes: Rapid microaggregation and migration of occupied receptors

Robert M. Smith, Melanie H. Cobb, Ora M. Rosen, Leonard Jarett

Journal:

Journal of Cellular Physiology

Year:

1985

Language:

english

File:

PDF, 2.58 MB

english, 1985

14

A comparison of protein synthetic patterns of MDCK cells grown in serum and hormonally defined serum-free medium

Douglas M. Jefferson, Chia-Ping H. Yang, Melanie H. Cobb, Walter N. Scott

Journal:

Journal of Cellular Physiology

Year:

1985

Language:

english

File:

PDF, 554 KB

english, 1985

15

Plate Fixation of Prostheses after Segmental Resection for Bone Tumours

Melanie J. Coathup, Justin P. Cobb, Peter S. Walker, Gordon W. Blunn

Journal:

Journal of Orthopaedic Research

Year:

2000

Language:

english

File:

PDF, 803 KB

english, 2000

16

Crystal structure of domain-swapped STE20 OSR1 kinase domain

Seung-Jae Lee, Melanie H. Cobb, Elizabeth J. Goldsmith

Journal:

Protein Science

Year:

2009

Language:

english

File:

PDF, 1.09 MB

english, 2009

17

Irreversible inhibition of sodium transport by the toad urinary bladder following photolysis of amiloride analogs

Melanie H. Cobb, W. N. Scott

Journal:

Cellular and Molecular Life Sciences

Year:

1981

Language:

english

File:

PDF, 237 KB

english, 1981

18

MAP kinases and their roles in pancreatic β-cells

Shih Khoo, Tara Beers Gibson, Don Arnette, Michael Lawrence, Bridgette January, Kathleen McGlynn, Colleen A. Vanderbilt, Steven C. Griffen, Michael S. German, Melanie H. Cobb

Journal:

Cell Biochemistry and Biophysics

Year:

2004

Language:

english

File:

PDF, 1.07 MB

english, 2004

19

Role of with-no-lysine [K] kinases in the pathogenesis of Gordon’s syndrome

Jian Xie, Leonard Craig, Melanie H. Cobb, Chou-Long Huang

Journal:

Pediatric Nephrology

Year:

2006

Language:

english

File:

PDF, 192 KB

english, 2006

20

WNK kinases and blood pressure control

Staci L. Deaton, Samarpita Sengupta, Melanie H. Cobb

Journal:

Current Hypertension Reports

Year:

2009

Language:

english

File:

PDF, 267 KB

english, 2009

21

Identification of an Activator of the Microtubule-Associated Protein 2 Kinases ERK1 and ERK2 in PC12 Cells Stimulated with Nerve Growth Factor or Bradykinin

Natalie G. Ahn, David J. Robbins, John W. Haycock, Rony Seger, Melanie H. Cobb, Edwin G. Krebs

Journal:

Journal of Neurochemistry

Year:

1992

Language:

english

File:

PDF, 1.36 MB

english, 1992

22

WNK1: analysis of protein kinase structure, downstream targets, and potential roles in hypertension

XU, Bing-e, LEE, Byung-Hoon, MIN, Xiaoshan, LENERTZ, Lisa, HEISE, Charles J, STIPPEC, Steve, GOLDSMITH, Elizabeth J, COBB, Melanie H

Journal:

Year:

2005

Language:

english

File:

PDF, 399 KB

english, 2005

23

Mxi2 promotes stimulus-independent ERK nuclear translocation

Casar, Berta, Sanz-Moreno, Victoria, Yazicioglu, Mustafa N, Rodríguez, Javier, Berciano, María T, Lafarga, Miguel, Cobb, Melanie H, Crespo, Piero

Journal:

The EMBO Journal

Year:

2007

Language:

english

File:

PDF, 403 KB

english, 2007

24

TAO kinases mediate activation of p38 in response to DNA damage

Raman, Malavika, Earnest, Svetlana, Zhang, Kai, Zhao, Yingming, Cobb, Melanie H

Journal:

The EMBO Journal

Year:

2007

Language:

english

File:

PDF, 274 KB

english, 2007

25

MAP kinases and their roles in pancreatic β-cells

Shih Khoo, Tara Beers Gibson, Don Arnette, Michael Lawrence, Bridgette January, Kathleen McGlynn, Colleen A. Vanderbilt, Steven C. Griffen, Michael S. German, Melanie H. Cobb

Journal:

Cell Biochemistry and Biophysics

Year:

2004

Language:

english

File:

PDF, 304 KB

english, 2004

26

Purification and properties of extracellular regulated kinase 1, an insulin-stimulated microtubule-associated protein 2 kinase

Boulton, Teri G., Gregory, Jill S., Cobb, Melanie H.

Journal:

Year:

1991

Language:

english

File:

PDF, 2.04 MB

english, 1991

27

The insulin receptor and tyrosine protein kinase activity

Melanie H. Cobb, Ora M. Rosen

Journal:

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

Year:

1984

Language:

english

File:

PDF, 683 KB

english, 1984

28

MAP Kinase Modules: Many Roads Home

Malavika Raman, Melanie H Cobb

Journal:

Current Biology

Year:

2003

Language:

english

File:

PDF, 54 KB

english, 2003

29

Crystal Structure of the Kinase Domain of WNK1, a Kinase that Causes a Hereditary Form of Hypertension

Xiaoshan Min, Byung-Hoon Lee, Melanie H Cobb, Elizabeth J Goldsmith

Journal:

Year:

2004

Language:

english

File:

PDF, 827 KB

english, 2004

30

Crystal Structure of the TAO2 Kinase Domain: Activation and Specificity of a Ste20p MAP3K

Tianjun Zhou, Malavika Raman, Yan Gao, Svetlana Earnest, Zhu Chen, Mischa Machius, Melanie H. Cobb, Elizabeth J. Goldsmith

Journal:

Year:

2004

Language:

english

File:

PDF, 565 KB

english, 2004

31

The Structure of the MAP2K MEK6 Reveals an Autoinhibitory Dimer

Xiaoshan Min, Radha Akella, Haixia He, John M. Humphreys, Susan E. Tsutakawa, Seung-Jae Lee, John A. Tainer, Melanie H. Cobb, Elizabeth J. Goldsmith

Journal:

Year:

2009

Language:

english

File:

PDF, 1.09 MB

english, 2009

32

MAP kinase pathways

Journal:

Progress in Biophysics and Molecular Biology

Year:

1999

Language:

english

File:

PDF, 174 KB

english, 1999

33

A constitutively active and nuclear form of the MAP kinase ERK2 is sufficient for neurite outgrowth and cell transformation

Megan J. Robinson, Stephen A. Stippec, Elizabeth Goldsmith, Michael A. White, Melanie H. Cobb

Journal:

Current Biology

Year:

1998

Language:

english

File:

PDF, 545 KB

english, 1998

34

Dimerization in MAP-kinase signaling

Melanie H Cobb, Elizabeth J Goldsmith

Journal:

Trends in Biochemical Sciences

Year:

2000

Language:

english

File:

PDF, 183 KB

english, 2000

35

Activity of the MAP kinase ERK2 is controlled by a flexible surface loop

Jiandong Zhang, Faming Zhang, Douglas Ebert, Melanie H Cobb, Elizabeth J Goldsmith

Journal:

Year:

1995

Language:

english

File:

PDF, 1.12 MB

english, 1995

36

MAP Kinase Becomes Stably Activated at Metaphase and Is Associated with Microtubule-Organizing Centers during Meiotic Maturation of Mouse Oocytes

Marie-Hélène Verlhac, Henri de Pennart, Bernard Maro, Melanie H. Cobb, Hugh J. Clarke

Journal:

Developmental Biology

Year:

1993

File:

PDF, 928 KB

1993

37

New Insights into the Control of MAP Kinase Pathways

Jessie English, Gray Pearson, Julie Wilsbacher, Jennifer Swantek, Mahesh Karandikar, Shuichan Xu, Melanie H. Cobb

Journal:

Experimental Cell Research

Year:

1999

Language:

english

File:

PDF, 113 KB

english, 1999

38

Crystallization and Preliminary X-ray Studies of Extracellular Signal-regulated Kinase-2/MAP Kinase with an Incorporated His-tag

Faming Zhang, David J. Robbins, Melanie H. Cobb, Elizabeth J. Goldsmith

Journal:

Journal of Molecular Biology

Year:

1993

File:

PDF, 137 KB

1993

39

Insulin-stimulated sodium transport in toad urinary bladder

Melanie H. Cobb, Chia-Ping H. Yang, James A. Brown Jr., Walter N. Scott

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1986

Language:

english

File:

PDF, 523 KB

english, 1986

40

A similar ribosomal protein S6 kinase activity is found in insulin-treated 3T3-L1 cells and chick embryo fibroblasts transformed by Rous sarcoma virus

Melanie H. Cobb, John G. Burr, Maurine E. Linder, Teri B. Gray, Jill S. Gregory

Journal:

Biochemical and Biophysical Research Communications

Year:

1986

Language:

english

File:

PDF, 1.03 MB

english, 1986

41

Extracellular signal-regulated kinases in T cells: Characterization of human ERK1 and ERK2 cDNAs

Hajime Owaki, Robert Makar, Teri G. Boulton, Melanie H. Cobb, Thomas D. Geppert

Journal:

Biochemical and Biophysical Research Communications

Year:

1992

Language:

english

File:

PDF, 599 KB

english, 1992

42

The MAP kinase ERK5 binds to and phosphorylates p90 RSK

Aarati Ranganathan, Gray W. Pearson, Carol A. Chrestensen, Thomas W. Sturgill, Melanie H. Cobb

Journal:

Archives of Biochemistry and Biophysics

Year:

2006

Language:

english

File:

PDF, 387 KB

english, 2006

43

TGF-β Regulation by Emilin1: New Links in the Etiology of Hypertension

Malavika Raman, Melanie H. Cobb

Journal:

Year:

2006

Language:

english

File:

PDF, 287 KB

english, 2006

44

MAP-ping Unconventional Protein-DNA Interactions

Elhadji M. Dioum, Eric M. Wauson, Melanie H. Cobb

Journal:

Year:

2009

Language:

english

File:

PDF, 315 KB

english, 2009

45

Exposing Contingency Plans for Kinase Networks

Aileen M. Klein, Elhadji M. Dioum, Melanie H. Cobb

Journal:

Year:

2010

Language:

english

File:

PDF, 279 KB

english, 2010

46

Starvation activates MAP kinase through the muscarinic acetylcholine pathway in Caenorhabditis elegans pharynx

Young-jai You, Jeongho Kim, Melanie Cobb, Leon Avery

Journal:

Cell Metabolism

Year:

2006

Language:

english

File:

PDF, 469 KB

english, 2006

47

Context-dependent regulation of NeuroD activity and protein accumulation

Christopher Dufton, Edoardo Marcora, Ji Hyung Chae, James McCullough, Jennifer Eby, Melissa Hausburg, Gretchen H. Stein, Shih Khoo, Melanie H. Cobb, Jacqueline E. Lee

Journal:

Molecular and Cellular Neuroscience

Year:

2005

Language:

english

File:

PDF, 393 KB

english, 2005

48

WNK1 Phosphorylates Synaptotagmin 2 and Modulates Its Membrane Binding

Byung-Hoon Lee, Xiaoshan Min, Charles J. Heise, Bing-e Xu, She Chen, Hongjun Shu, Kate Luby-Phelps, Elizabeth J. Goldsmith, Melanie H. Cobb

Journal:

Year:

2004

Language:

english

File:

PDF, 616 KB

english, 2004

49

FAK Phosphorylation by ERK Primes Ras-Induced Tyrosine Dephosphorylation of FAK Mediated by PIN1 and PTP-PEST

Yanhua Zheng, Yan Xia, David Hawke, Maxime Halle, Michel L. Tremblay, Xiang Gao, Xiao Zhen Zhou, Kenneth Aldape, Melanie H. Cobb, Keping Xie, Jie He, Zhimin Lu

Journal:

Year:

2009

Language:

english

File:

PDF, 1.97 MB

english, 2009

50

Expression and characterization of MAP kinases in bacteria

Charles J. Heise, Melanie H. Cobb

Journal:

Year:

2006

Language:

english

File:

PDF, 153 KB

english, 2006